Clinical efficiency of dynamic observation of patients with epidermal dysplasia of the skin.

ABSTRACT

OBJECTIVE: Introduction: Non-melanoma skin cancer is the most common type of cancer among the population of Ukraine. The aim: The study of clinical efficacy of dynamic observation of patients with epidermal dysplasia of the skin. PATIENTS AND METHODS: Materials and methods: To study epidermal dysplasia of the skin there was used identifying information of patients, who were under dynamic observation of dermatologists of the State Scientific Institution "Research and Practical Centre of Preventive and Clinical Medicine" of the State Administration in 2013-2017. RESULTS: Results: In 2013-2017, under our supervision there were 245 patients with epidermal dysplasia of the skin, including 66 (27.0%) patients with invasive squamous cell carcinoma, 71 (29.0%) patients with squamous cell carcinoma in situ and 108 (44.0%) patients with actinic keratosis. It has been established that the level of annual progression of epidermal dysplasia of the skin in patients with actinic keratosis was 1.4%, in patients with squamous cell carcinoma in situ and invasive squamous cell carcinoma - 3.22% and 0.86%, respectively. CONCLUSION: Conclusions: It has been found that the level of annual progression of epidermal dysplasia of the skin in patients with a combined course of the above listed pathology of the skin was significantly (p≤0.05) higher and amounted to 8.8%.