Iodine-Induced Fetal Hypothyroidism: Diagnosis and Treatment with Intra-Amniotic Levothyroxine.
Horm Res Paediatr
; 90(6): 419-423, 2018.
Article
em En
| MEDLINE
| ID: mdl-29791909
ABSTRACT
BACKGROUND:
Iodine is necessary for fetal thyroid development. Excess maternal intake of iodine can cause fetal hypothyroidism due to the inability to escape from the Wolff-Chaikoff effect in utero. CASE REPORT We report a case of fetal hypothyroid goiter secondary to inadvertent excess maternal iodine ingestion from infertility supplements. The fetus was successfully treated with intra-amniotic levothyroxine injections. Serial fetal blood sampling confirmed fetal escape from the Wolff-Chaikoff effect in the mid third trimester. Early hearing test and neurodevelopmental milestones were normal.CONCLUSION:
Intra-amniotic treatment of fetal hypothyroidism may decrease the rate of impaired neurodevelopment and sensorineural hearing loss.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Tiroxina
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Hipotireoidismo Congênito
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Doenças Fetais
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Bócio
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Iodo
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article