PM2.5 induces autophagy-mediated cell death via NOS2 signaling in human bronchial epithelium cells.

Zhu, Xiao-Ming; Wang, Qin; Xing, Wei-Wei; Long, Min-Hui; Fu, Wen-Liang; Xia, Wen-Rong; Jin, Chen; Guo, Ning; Xu, Dong-Qun; Xu, Dong-Gang

Zhu, Xiao-Ming; Wang, Qin; Xing, Wei-Wei; Long, Min-Hui; Fu, Wen-Liang; Xia, Wen-Rong; Jin, Chen; Guo, Ning; Xu, Dong-Qun; Xu, Dong-Gang.

Afiliação

Zhu XM; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Wang Q; Institute for Environmental Health and Related Product Safety, China, CDC, Beijing, 100021, China.
Xing WW; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Long MH; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Fu WL; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Xia WR; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Jin C; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Guo N; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.
Xu DQ; Institute for Environmental Health and Related Product Safety, China, CDC, Beijing, 100021, China.
Xu DG; Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Beijing, 100850, China.

Int J Biol Sci ; 14(5): 557-564, 2018.

Article em En | MEDLINE | ID: mdl-29805307

Assuntos

Autofagia; Células Epiteliais/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Material Particulado/efeitos adversos; Poluentes Atmosféricos/efeitos adversos; Apoptose; Brônquios/citologia; Morte Celular; Células Epiteliais/citologia; Epitélio/metabolismo; Humanos; Inflamação; Interleucina-6/metabolismo; Pulmão/citologia; Estresse Oxidativo; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais; Regulação para Cima

Palavras-chave

Autophagy-mediated cell death; Clinic intervention; Human bronchial epithelium cells; NOS2 signaling; Particulate matters two point five (PM2.5)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Células Epiteliais / Óxido Nítrico Sintase Tipo II / Material Particulado Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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