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One bis-indole alkaloid-voacamine from Voacanga africana Stapf: biological activity evaluation of PTP1B in vitro utilizing enzymology method based on SPRi expriment.
Wang, Yan-Qiu; Li, Hong-Xiang; Liu, Xiao-Chun; Zhao, Jin-Shuang; Liu, Rong-Qiang; Huai, Wen-Ying; Ding, Wei-Jun; Zhang, Tian-E; Deng, Yun.
Afiliação
  • Wang YQ; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Li HX; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Liu XC; Marine Biomedical Research Institute of Qingdao , Qingdao , P R China.
  • Zhao JS; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Liu RQ; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Huai WY; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Ding WJ; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Zhang TE; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
  • Deng Y; School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine , Chengdu , P R China.
Nat Prod Res ; 33(23): 3459-3463, 2019 Dec.
Article em En | MEDLINE | ID: mdl-29852800
ABSTRACT
One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding promoting activity to PTP1B.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ressonância de Plasmônio de Superfície / Voacanga / Proteína Tirosina Fosfatase não Receptora Tipo 1 / Ibogaína Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ressonância de Plasmônio de Superfície / Voacanga / Proteína Tirosina Fosfatase não Receptora Tipo 1 / Ibogaína Idioma: En Ano de publicação: 2019 Tipo de documento: Article