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The co-existence of NS5A and NS5B resistance-associated substitutions is associated with virologic failure in Hepatitis C Virus genotype 1 patients treated with sofosbuvir and ledipasvir.
Mawatari, Seiichi; Oda, Kohei; Tabu, Kazuaki; Ijuin, Sho; Kumagai, Kotaro; Fujisaki, Kunio; Hashiguchi, Masafumi; Inada, Yukiko; Uto, Hirofumi; Hiramine, Yasunari; Kure, Takeshi; Hori, Takeshi; Taniyama, Oki; Kasai, Ai; Tamai, Tsutomu; Moriuchi, Akihiro; Ido, Akio.
Afiliação
  • Mawatari S; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Oda K; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Tabu K; Department of HGF Tissue Repair and Regenerative Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Ijuin S; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Kumagai K; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Fujisaki K; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Hashiguchi M; Department of Gastroenterology and Hepatology, Kagoshima City Hospital, Uearata-cho Kagoshima, Japan.
  • Inada Y; Department of Hepatology, Kirishima Medical Center, Kirishima, Hayato-cho, Kirishima, Kagoshima, Japan.
  • Uto H; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Hiramine Y; Department of Hepatology, Kirishima Medical Center, Kirishima, Hayato-cho, Kirishima, Kagoshima, Japan.
  • Kure T; Center for Digestive and Liver Diseases, Miyazaki Medical Center Hospital, Takamatsu-cho, Miyazaki, Japan.
  • Hori T; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Taniyama O; Center for Digestive and Liver Diseases, Miyazaki Medical Center Hospital, Takamatsu-cho, Miyazaki, Japan.
  • Kasai A; Department of Internal Medicine, Kagoshima Kouseiren Hospital, Tenpozan-cho, Kagoshima, Japan.
  • Tamai T; Digestive and Lifestyle Diseases, Department of Human and Environmental Sciences,Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.
  • Moriuchi A; Department of Internal Medicine, Kagoshima Kouseiren Hospital, Tenpozan-cho, Kagoshima, Japan.
  • Ido A; Department of Gastroenterology and Hepatology, Kagoshima City Hospital, Uearata-cho Kagoshima, Japan.
PLoS One ; 13(6): e0198642, 2018.
Article em En | MEDLINE | ID: mdl-29856885
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uridina Monofosfato / Benzimidazóis / Proteínas não Estruturais Virais / Hepacivirus / Hepatite C Crônica / Farmacorresistência Viral Múltipla / Fluorenos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uridina Monofosfato / Benzimidazóis / Proteínas não Estruturais Virais / Hepacivirus / Hepatite C Crônica / Farmacorresistência Viral Múltipla / Fluorenos Idioma: En Ano de publicação: 2018 Tipo de documento: Article