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Dosing optimization of CCR4 immunotoxin for improved depletion of CCR4+ Treg in nonhuman primates.
Wang, Zhaohui; Louras, Nathan J; Lellouch, Alexandre G; Pratts, Shannon G; Zhang, Huiping; Wang, Haoyu; Huang, Christene A; Cetrulo, Curtis L; Madsen, Joren C; Sachs, David H; Wang, Zhirui.
Afiliação
  • Wang Z; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Louras NJ; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Lellouch AG; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Pratts SG; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Zhang H; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Wang H; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Huang CA; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Cetrulo CL; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Madsen JC; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Sachs DH; Division of Cardiac Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Wang Z; Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Mol Oncol ; 12(8): 1374-1382, 2018 08.
Article em En | MEDLINE | ID: mdl-29873181

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunotoxinas / Linfócitos T Reguladores / Toxina Diftérica / Receptores CCR4 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunotoxinas / Linfócitos T Reguladores / Toxina Diftérica / Receptores CCR4 Idioma: En Ano de publicação: 2018 Tipo de documento: Article