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Phase 1/1b dose escalation and expansion study of BEZ235, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumors including patients with advanced breast cancer.
Rodon, Jordi; Pérez-Fidalgo, Alejandro; Krop, Ian E; Burris, Howard; Guerrero-Zotano, Angel; Britten, Carolyn D; Becerra, Carlos; Schellens, Jan; Richards, Donald A; Schuler, Martin; Abu-Khalaf, Maysa; Johnson, Faye M; Ranson, Malcolm; Edenfield, Jeff; Silva, Antonio P; Hackl, Wolfgang; Quadt, Cornelia; Demanse, David; Duval, Vincent; Baselga, Jose.
Afiliação
  • Rodon J; Medical Oncology Department, Vall d'Hebrón University Hospital, Barcelona, Spain. jrodon@vhio.net.
  • Pérez-Fidalgo A; INCLIVA Biomedical Research Institute, Valencia, Spain.
  • Krop IE; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Burris H; Sarah Cannon Research Institute, Nashville, TN, USA.
  • Guerrero-Zotano A; Instituto Valenciano de Oncología, Valencia, Spain.
  • Britten CD; Medical University of South Carolina, Charleston, SC, USA.
  • Becerra C; Texas Oncology, Dallas, TX, USA.
  • Schellens J; The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Richards DA; Texas Oncology, Dallas, TX, USA.
  • Schuler M; West German Cancer Center, University Hospital Essen, Essen, Germany.
  • Abu-Khalaf M; Thomas Jefferson University, Philadelphia, PA, USA.
  • Johnson FM; MD Anderson Cancer Center, Houston, TX, USA.
  • Ranson M; Manchester University, Manchester, UK.
  • Edenfield J; Greenville Memorial Hospital, Greenville, SC, USA.
  • Silva AP; Novartis Pharma AG, Basel, Switzerland.
  • Hackl W; Novartis Pharma AG, Basel, Switzerland.
  • Quadt C; Novartis Pharma AG, Basel, Switzerland.
  • Demanse D; Novartis Pharma AG, Basel, Switzerland.
  • Duval V; Novartis Pharma AG, Basel, Switzerland.
  • Baselga J; Memorial Sloan Kettering Cancer Center, New York, USA.
Cancer Chemother Pharmacol ; 82(2): 285-298, 2018 08.
Article em En | MEDLINE | ID: mdl-29882016
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Neoplasias da Mama / Imidazóis / Neoplasias Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Neoplasias da Mama / Imidazóis / Neoplasias Idioma: En Ano de publicação: 2018 Tipo de documento: Article