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Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA.
Hirsch, Mauro Mozael; Deckmann, Iohanna; Fontes-Dutra, Mellanie; Bauer-Negrini, Guilherme; Nunes, Gustavo Della-Flora; Nunes, Walquiria; Rabelo, Bruna; Riesgo, Rudimar; Margis, Rogerio; Bambini-Junior, Victorio; Gottfried, Carmem.
Afiliação
  • Hirsch MM; Translational Group in Autism Spectrum Disorder - GETTEA, Clinical Hospital of Porto Alegre, RS, Brazil.
  • Deckmann I; Department of Biochemistry, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, RS, Brazil.
  • Fontes-Dutra M; Brazilian National Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Rio de Janeiro, Brazil.
  • Bauer-Negrini G; Translational Group in Autism Spectrum Disorder - GETTEA, Clinical Hospital of Porto Alegre, RS, Brazil.
  • Nunes GD; Department of Biochemistry, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, RS, Brazil.
  • Nunes W; Brazilian National Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Rio de Janeiro, Brazil.
  • Rabelo B; Translational Group in Autism Spectrum Disorder - GETTEA, Clinical Hospital of Porto Alegre, RS, Brazil.
  • Riesgo R; Department of Biochemistry, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, RS, Brazil.
  • Margis R; Brazilian National Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM), Rio de Janeiro, Brazil.
  • Bambini-Junior V; Translational Group in Autism Spectrum Disorder - GETTEA, Clinical Hospital of Porto Alegre, RS, Brazil.
  • Gottfried C; Department of Biochemistry, Federal University of Rio Grande do Sul - UFRGS, Porto Alegre, RS, Brazil.
Data Brief ; 18: 1433-1440, 2018 Jun.
Article em En | MEDLINE | ID: mdl-29904648
ABSTRACT
This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents' experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article