Determinants of Base-Pair Substitution Patterns Revealed by Whole-Genome Sequencing of DNA Mismatch Repair Defective <i>Escherichia coli</i>.

Foster, Patricia L; Niccum, Brittany A; Popodi, Ellen; Townes, Jesse P; Lee, Heewook; MohammedIsmail, Wazim; Tang, Haixu

Determinants of Base-Pair Substitution Patterns Revealed by Whole-Genome Sequencing of DNA Mismatch Repair Defective Escherichia coli.

Foster, Patricia L; Niccum, Brittany A; Popodi, Ellen; Townes, Jesse P; Lee, Heewook; MohammedIsmail, Wazim; Tang, Haixu.

Afiliação

Foster PL; Department of Biology, Indiana University, Bloomington, Indiana 47405 plfoster@indiana.edu.
Niccum BA; Department of Biology, Indiana University, Bloomington, Indiana 47405.
Popodi E; Department of Biology, Indiana University, Bloomington, Indiana 47405.
Townes JP; Department of Biology, Indiana University, Bloomington, Indiana 47405.
Lee H; School of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47405.
MohammedIsmail W; School of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47405.
Tang H; School of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana 47405.

Genetics ; 209(4): 1029-1042, 2018 08.

Article em En | MEDLINE | ID: mdl-29907647

Assuntos

Substituição de Aminoácidos; Reparo de Erro de Pareamento de DNA; Escherichia coli/genética; Sequenciamento Completo do Genoma/métodos; Replicação do DNA; Genoma Bacteriano; Mutação Puntual

Palavras-chave

DNA polymerase fidelity; DNA replication accuracy; mismatch repair; mutation accumulation; mutation hotspots

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Substituição de Aminoácidos / Escherichia coli / Reparo de Erro de Pareamento de DNA / Sequenciamento Completo do Genoma Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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