Comparative efficacies of topical antiseptic eardrops against biofilms from methicillin-resistant Staphylococcus aureus and quinolone-resistant Pseudomonas aeruginosa.
J Laryngol Otol
; 132(6): 519-522, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-29909794
ABSTRACT
OBJECTIVE:
The present study aimed to compare the anti-biofilm activities of four commonly available antiseptic eardrops against biofilms from methicillin-resistant Staphylococcus aureus and quinolone-resistant Pseudomonas aeruginosa in vitro.METHODS:
The anti-biofilm activities of 50 per cent Burow's solution, vinegar with water (11), 2 per cent acetic acid solution, and 4 per cent boric acid solution were evaluated using biofilm assays. Additionally, the anti-biofilm activities of the four antiseptic solutions against tympanostomy tube biofilms were compared using a scanning electron microscope.RESULTS:
The inhibition of biofilm formation from methicillin-resistant S aureus and quinolone-resistant P aeruginosa occurred after treatment with 4 per cent boric acid solution, 2 per cent acetic acid solution, and vinegar with water (11). However, 50 per cent Burow's solution did not exhibit effective anti-biofilm activity.CONCLUSION:
The results indicate that 4 per cent boric acid solution and vinegar with water (11) are potent inhibitors of biofilms from methicillin-resistant S aureus and quinolone-resistant P aeruginosa, and provide safe pH levels for avoiding ototoxicity.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Próteses e Implantes
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Pseudomonas aeruginosa
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Ácidos Bóricos
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Biofilmes
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Ácido Acético
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Staphylococcus aureus Resistente à Meticilina
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Acetatos
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Anti-Infecciosos Locais
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article