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Enhanced Precision of Circular Dichroism Spectral Measurements Permits Detection of Subtle Higher Order Structural Changes in Therapeutic Proteins.
Barnett, Gregory V; Balakrishnan, Gurusamy; Chennamsetty, Naresh; Meengs, Brent; Meyer, Jeffery; Bongers, Jacob; Ludwig, Richard; Tao, Li; Das, Tapan K; Leone, Anthony; Kar, Sambit R.
Afiliação
  • Barnett GV; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534. Electronic address: gvb2117@gmail.com.
  • Balakrishnan G; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Chennamsetty N; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Meengs B; Analytical Development, ZymoGenetics (A Bristol-Myers Squibb Company), Seattle, Washington 98102.
  • Meyer J; Analytical Development, ZymoGenetics (A Bristol-Myers Squibb Company), Seattle, Washington 98102.
  • Bongers J; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Ludwig R; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Tao L; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Das TK; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Leone A; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
  • Kar SR; Biologics Molecular and Analytical Development, Bristol-Myers Squibb, Hopewell, New Jersey 08534.
J Pharm Sci ; 107(10): 2559-2569, 2018 10.
Article em En | MEDLINE | ID: mdl-29913140
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Proteínas Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Proteínas Idioma: En Ano de publicação: 2018 Tipo de documento: Article