Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD.

Shenouda, Marc; Zhang, Ashley B; Weichert, Anna; Robertson, Janice

Shenouda, Marc; Zhang, Ashley B; Weichert, Anna; Robertson, Janice.

Afiliação

Shenouda M; Tanz Centre for Research in Neurodegenerative Diseases and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5T 2S8, Canada.
Zhang AB; Tanz Centre for Research in Neurodegenerative Diseases and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5T 2S8, Canada.
Weichert A; Tanz Centre for Research in Neurodegenerative Diseases and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5T 2S8, Canada.
Robertson J; Tanz Centre for Research in Neurodegenerative Diseases and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5T 2S8, Canada. jan.robertson@utoronto.ca.

Adv Neurobiol ; 20: 239-263, 2018.

Article em En | MEDLINE | ID: mdl-29916022

Assuntos

Esclerose Lateral Amiotrófica/metabolismo; Encéfalo/metabolismo; Proteínas de Ligação a DNA/metabolismo; Degeneração Lobar Frontotemporal/metabolismo; Esclerose Lateral Amiotrófica/genética; Esclerose Lateral Amiotrófica/patologia; Encéfalo/patologia; Proteínas de Ligação a DNA/genética; Degeneração Lobar Frontotemporal/genética; Degeneração Lobar Frontotemporal/patologia; Humanos; Mutação

Palavras-chave

ALS; FTLD; Granules; RNA; TDP-43

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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