Individualized texting for adherence building (iTAB) for methamphetamine users living with HIV: A pilot randomized clinical trial.
Drug Alcohol Depend
; 189: 154-160, 2018 08 01.
Article
em En
| MEDLINE
| ID: mdl-29958127
ABSTRACT
BACKGROUND:
Methamphetamine (METH) use poses a barrier to antiretroviral therapy (ART) adherence. We evaluated the efficacy of the individualized texting for adherence building (iTAB) intervention among persons living with HIV (PLWH) who meet criteria for METH use disorder. We examined daily associations between ART adherence and text-reported METH use and depressed mood.METHODS:
We conducted a single site, 2-arm, 6-week, pilot randomized clinical trial comparing a personalized, bidirectional, text messaging system (iTAB; nâ¯=â¯50) to an active control condition (nâ¯=â¯25). All participants received adherence psychoeducation and daily texts assessing METH use and depressed mood. The iTAB group received personalized daily ART reminder texts. ART adherence was monitored using Medication Event Monitoring System (MEMS) caps.RESULTS:
Response rates to daily ART reminder texts were high (79%), with good concordance between MEMS-derived and text-reported ART adherence (pâ¯<â¯.001). Intervention groups did not differ in MEMS-derived ART adherence (68% iTAB, 70% active control; pâ¯=â¯.68); however, participants in the iTAB group had fewer METH use days (median 14.4 iTAB, 22.0 active control; pâ¯=â¯.05). Text-reported METH use, but not depressed mood, was associated with poorer MEMS-derived ART adherence.CONCLUSIONS:
High text response rates and good concordance between MEMS-derived and text-reported adherence suggests text messaging is a feasible intervention delivery approach that provides a valid indication of ART adherence. Reductions in METH use among iTAB participants suggest daily health reminders may help attenuate substance use. Further research is needed to substantiate daily text messaging as a harm reduction approach.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
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Fármacos Anti-HIV
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Transtornos Relacionados ao Uso de Anfetaminas
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Adesão à Medicação
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Envio de Mensagens de Texto
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Metanfetamina
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article