Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-<i>&#954;</i>B Pathway.

Wu, Ling-Yun; Ye, Zhen-Nan; Zhuang, Zong; Gao, Yongyue; Tang, Chao; Zhou, Chen-Hui; Wang, Chun-Xi; Zhang, Xiang-Sheng; Xie, Guang-Bin; Liu, Jing-Peng; Zhou, Meng-Liang; Hang, Chun-Hua; Shi, Ji-Xin

Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway.

Wu, Ling-Yun; Ye, Zhen-Nan; Zhuang, Zong; Gao, Yongyue; Tang, Chao; Zhou, Chen-Hui; Wang, Chun-Xi; Zhang, Xiang-Sheng; Xie, Guang-Bin; Liu, Jing-Peng; Zhou, Meng-Liang; Hang, Chun-Hua; Shi, Ji-Xin.

Afiliação

Wu LY; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Ye ZN; Department of Neurosurgery, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province 510260, China.
Zhuang Z; Department of Neurosurgery, Jinling Hospital, School of Medicine, Southern Medical University (Guangzhou), Nanjing, Jiangsu Province 210002, China.
Gao Y; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Tang C; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Zhou CH; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Wang CX; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Zhang XS; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Xie GB; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Liu JP; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Zhou ML; Department of Neurosurgery, Jinling Hospital, School of Medicine, Southern Medical University (Guangzhou), Nanjing, Jiangsu Province 210002, China.
Hang CH; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.
Shi JX; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East ZhongShan Road, Nanjing, Jiangsu Province 210002, China.

Behav Neurol ; 2018: 1960106, 2018.

Article em En | MEDLINE | ID: mdl-29971136

Assuntos

Genisteína/farmacologia; Hemorragia Subaracnóidea/tratamento farmacológico; Proteínas Adaptadoras de Transdução de Sinal/efeitos dos fármacos; Animais; Apoptose/efeitos dos fármacos; Modelos Animais de Doenças; Genisteína/metabolismo; Inflamação; Masculino; Fator 88 de Diferenciação Mieloide/efeitos dos fármacos; NF-kappa B/efeitos dos fármacos; Neurônios/metabolismo; Fármacos Neuroprotetores/farmacologia; Ratos; Ratos Sprague-Dawley; Transdução de Sinais/efeitos dos fármacos; Receptores Toll-Like/efeitos dos fármacos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Subaracnóidea / Genisteína Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Subaracnóidea / Genisteína Idioma: En Ano de publicação: 2018 Tipo de documento: Article