Olive leaf extract counteracts epithelial to mesenchymal transition process induced by peritoneal dialysis, through the inhibition of TGFß1 signaling.

Lupinacci, S; Perri, Anna; Toteda, G; Vizza, D; Puoci, F; Parisi, O I; Giordano, F; Lofaro, D; La Russa, A; Bonofiglio, M; Bonofiglio, R

Lupinacci, S; Perri, Anna; Toteda, G; Vizza, D; Puoci, F; Parisi, O I; Giordano, F; Lofaro, D; La Russa, A; Bonofiglio, M; Bonofiglio, R.

Afiliação

Lupinacci S; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.
Perri A; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy. perria71@gmail.com.
Toteda G; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.
Vizza D; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.
Puoci F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Parisi OI; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Giordano F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Lofaro D; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.
La Russa A; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.
Bonofiglio M; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.
Bonofiglio R; "Kidney and Transplantation" Research Center, Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, F. Migliori, 1, 87100, Cosenza, CS, Italy.

Cell Biol Toxicol ; 35(2): 95-109, 2019 04.

Article em En | MEDLINE | ID: mdl-29978330

Assuntos

Transição Epitelial-Mesenquimal/efeitos dos fármacos; Olea/química; Diálise Peritoneal/efeitos adversos; Extratos Vegetais/farmacologia; Fator de Crescimento Transformador beta1/metabolismo; Antígenos de Diferenciação/metabolismo; Caderinas/metabolismo; Linhagem Celular; Membrana Celular/efeitos dos fármacos; Membrana Celular/metabolismo; Glucosídeos/metabolismo; Humanos; Glucosídeos Iridoides; Iridoides/análise; Fenóis/metabolismo; Álcool Feniletílico/análogos & derivados; Álcool Feniletílico/metabolismo; Transdução de Sinais/efeitos dos fármacos; Proteínas Smad Reguladas por Receptor/metabolismo

Palavras-chave

E-cadherin promoter; EMT; Olive leaves; Peritoneal dialysis; Polyphenols

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Diálise Peritoneal / Olea / Fator de Crescimento Transformador beta1 / Transição Epitelial-Mesenquimal Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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