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Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABAA Receptors.
Siebert, David C B; Bampali, Konstantina; Puthenkalam, Roshan; Varagic, Zdravko; Sarto-Jackson, Isabella; Scholze, Petra; Sieghart, Werner; Mihovilovic, Marko D; Schnürch, Michael; Ernst, Margot.
Afiliação
  • Siebert DCB; Institute of Applied Synthetic Chemistry, TU Wien , Getreidemarkt 9/163 , 1060 Vienna , Austria.
  • Bampali K; Department of Molecular Neurosciences , Center for Brain Research, Medical University Vienna , Spitalgasse 4 , 1090 Vienna , Austria.
  • Puthenkalam R; Department of Molecular Neurosciences , Center for Brain Research, Medical University Vienna , Spitalgasse 4 , 1090 Vienna , Austria.
  • Varagic Z; Department of Molecular Neurosciences , Center for Brain Research, Medical University Vienna , Spitalgasse 4 , 1090 Vienna , Austria.
  • Sarto-Jackson I; Konrad Lorenz Institute for Evolution and Cognition Research , Altenberg , Austria.
  • Scholze P; Department of Pathobiology of the Nervous System, Center for Brain Research , Medical University of Vienna , Spitalgasse 4 , 1090 Vienna , Austria.
  • Sieghart W; Department of Molecular Neurosciences , Center for Brain Research, Medical University Vienna , Spitalgasse 4 , 1090 Vienna , Austria.
  • Mihovilovic MD; Institute of Applied Synthetic Chemistry, TU Wien , Getreidemarkt 9/163 , 1060 Vienna , Austria.
  • Schnürch M; Institute of Applied Synthetic Chemistry, TU Wien , Getreidemarkt 9/163 , 1060 Vienna , Austria.
  • Ernst M; Department of Molecular Neurosciences , Center for Brain Research, Medical University Vienna , Spitalgasse 4 , 1090 Vienna , Austria.
ACS Chem Biol ; 13(8): 2040-2047, 2018 08 17.
Article em En | MEDLINE | ID: mdl-29989390
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flumazenil / Receptores de GABA-A Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flumazenil / Receptores de GABA-A Idioma: En Ano de publicação: 2018 Tipo de documento: Article