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Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity.
Koch, Pierre; Brunschweiger, Andreas; Namasivayam, Vigneshwaran; Ullrich, Stefan; Maruca, Annalisa; Lazzaretto, Beatrice; Küppers, Petra; Hinz, Sonja; Hockemeyer, Jörg; Wiese, Michael; Heer, Jag; Alcaro, Stefano; Kiec-Kononowicz, Katarzyna; Müller, Christa E.
Afiliação
  • Koch P; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Brunschweiger A; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Namasivayam V; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Ullrich S; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Maruca A; Dipartimento di Scienze della Salute, Università degli Studi "Magna Græcia" di Catanzaro, Catanzaro, Italy.
  • Lazzaretto B; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Küppers P; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Hinz S; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Hockemeyer J; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Wiese M; Pharmaceutical Institute, Pharmaceutical Chemistry II, University of Bonn, Bonn, Germany.
  • Heer J; UCB Celltech, UCB Pharma S.A., Slough, United Kingdom.
  • Alcaro S; Dipartimento di Scienze della Salute, Università degli Studi "Magna Græcia" di Catanzaro, Catanzaro, Italy.
  • Kiec-Kononowicz K; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
  • Müller CE; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
Front Chem ; 6: 206, 2018.
Article em En | MEDLINE | ID: mdl-29998095
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article