Association between asthma and migraine: A cross-sectional study of over 110 000 adolescents.
Clin Respir J
; 12(10): 2491-2496, 2018 Oct.
Article
em En
| MEDLINE
| ID: mdl-30004178
ABSTRACT
BACKGROUND:
Epidemiological studies have reported an association between asthma and migraine, mainly in adults.OBJECTIVE:
To examine the association between specialist-diagnosed asthma and migraine among adolescents.METHODS:
The electronic database of a recruitment center was retrospectively searched for all 17-year-old draftees during the years 1987-2010. Diagnoses of asthma and migraine were made by certified specialists. The prevalence of migraine was compared among draftees with and without asthma. Covariate data on socio-demographics and associated medical conditions were recorded.RESULTS:
A total of 113 671 adolescents were available for analysis. Asthma was diagnosed among 4.0% and migraine among 1.9%. Migraine was significantly more prevalent among adolescents with asthma [174 of the 4581 subjects (3.8%)] compared to those without asthma [1946 of the 109 090 (1.8%)] [OR = 2.17 (95% CI 1.86-2.55; P < 0.001)]. Rates of migraine among subjects with and without allergic rhinitis were 6.3% and 1.7%, respectively [OR = 4.04 (95% CI 3.58-4.56; P < 0.001)]. On multivariate analysis, there was a significant association between migraine and both asthma [OR = 1.42 (95% CI 1.19-1.68)] and allergic rhinitis [OR = 3.18 (95% CI 2.80-3.63)]. Other factors significantly associated with migraine were female gender, urban area of residence, recent immigration to Israel, having three or fewer siblings, and abnormal body mass index.CONCLUSION:
Clinicians should be aware that asthma and allergic rhinitis are potential risk factors for migraine in adolescents. A combined finding of these conditions and recurrent headache is highly suggestive of migraine and warrants a different diagnosis and treatment approach from sinusitis.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Asma
/
Hipersensibilidade
/
Transtornos de Enxaqueca
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article