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Porphyrins and related macrocycles: Combining photosensitization with radio- or optical-imaging for next generation theranostic agents.
Sandland, Jordon; Malatesti, Nela; Boyle, Ross.
Afiliação
  • Sandland J; School of Mathematics and Physical Sciences, Faculty of Science and Engineering, University of Hull, Hull, UK; Positron Emission Tomography Centre, University of Hull, Hull, UK.
  • Malatesti N; Department of Biotechnology, University of Rijeka, Rijeka, Croatia.
  • Boyle R; School of Mathematics and Physical Sciences, Faculty of Science and Engineering, University of Hull, Hull, UK. Electronic address: r.w.boyle@hull.ac.uk.
Photodiagnosis Photodyn Ther ; 23: 281-294, 2018 Sep.
Article em En | MEDLINE | ID: mdl-30009949
ABSTRACT
This review summarises recent research into combining the photosensitizing properties of porphyrins with imaging techniques such as PET and NIR fluorescence for so called "theranostic" applications, which combine biomedical imaging and therapeutic potential into a single administered substance. The photophysical mechanisms of both the therapeutic and diagnostic properties of porphyrins are discussed, as well as key characteristics that are required in order to deliver the most effective treatment.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Porfirinas / Diagnóstico por Imagem / Fármacos Fotossensibilizantes / Nanomedicina Teranóstica / Luz Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Porfirinas / Diagnóstico por Imagem / Fármacos Fotossensibilizantes / Nanomedicina Teranóstica / Luz Idioma: En Ano de publicação: 2018 Tipo de documento: Article