Prognostic utility of neutrophil-to-lymphocyte and platelets-to-lymphocyte ratio in predicting biochemical recurrence post robotic prostatectomy.
Biomark Med
; 12(8): 841-848, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-30019909
ABSTRACT
AIM:
Utility of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting biochemical recurrence (BCR) in patients with localized prostate cancer. MATERIALS &METHODS:
Retrospective analysis of patients operated by robot-assisted radical prostatectomy. Variables included were NLR, PLR pre-operative prostate specific antigen, pathological Gleason score, surgical margins status, extracapsular extension, seminal vesical invasion, and lymph node status.RESULTS:
Out of 321 patients, no association between NLR or PLR and BCR was detected. Predictors of BCR were pathological Gleason score, extracapsular extension and positive surgical margins. On multivariate analysis, the Gleason Score, extracapsular extension and positive surgical margins remained the only predictors of BCR.CONCLUSION:
Neither elevated NLR nor PLR predicted an increased risk of BCR.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Prostatectomia
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Neoplasias da Próstata
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Linfócitos
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Procedimentos Cirúrgicos Robóticos
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Recidiva Local de Neoplasia
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Neutrófilos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article