Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability.

Kunisawa, Kazuo; Shimizu, Takeshi; Kushima, Itaru; Aleksic, Branko; Mori, Daisuke; Osanai, Yasuyuki; Kobayashi, Kenta; Taylor, Anna M; Bhat, Manzoor A; Hayashi, Akiko; Baba, Hiroko; Ozaki, Norio; Ikenaka, Kazuhiro

Kunisawa, Kazuo; Shimizu, Takeshi; Kushima, Itaru; Aleksic, Branko; Mori, Daisuke; Osanai, Yasuyuki; Kobayashi, Kenta; Taylor, Anna M; Bhat, Manzoor A; Hayashi, Akiko; Baba, Hiroko; Ozaki, Norio; Ikenaka, Kazuhiro.

Afiliação

Kunisawa K; Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Okazaki, Japan.
Shimizu T; SOKENDAI (The Graduate University for Advanced Studies), Okazaki, Japan.
Kushima I; Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Okazaki, Japan.
Aleksic B; SOKENDAI (The Graduate University for Advanced Studies), Okazaki, Japan.
Mori D; Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Osanai Y; Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kobayashi K; Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Taylor AM; Brain and Mind Research Center, Nagoya University, Nagoya, Japan.
Bhat MA; Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Okazaki, Japan.
Hayashi A; SOKENDAI (The Graduate University for Advanced Studies), Okazaki, Japan.
Baba H; SOKENDAI (The Graduate University for Advanced Studies), Okazaki, Japan.
Ozaki N; Section of Viral Vector Development, National Institute for Physiological Sciences, Okazaki, Japan.
Ikenaka K; Department of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA.

J Neurochem ; 147(3): 395-408, 2018 11.

Article em En | MEDLINE | ID: mdl-30025158

Assuntos

Aquaporina 3/metabolismo; Neurônios/metabolismo; Esquizofrenia/metabolismo; Animais; Axônios/metabolismo; Axônios/patologia; Caspase 3/genética; Caspase 3/metabolismo; Moléculas de Adesão Celular/biossíntese; Moléculas de Adesão Celular/genética; Sobrevivência Celular; Variações do Número de Cópias de DNA; Dependovirus/genética; Feminino; Duplicação Gênica; Expressão Gênica; Masculino; Camundongos; Camundongos Knockout; Camundongos Transgênicos; Córtex Motor/metabolismo; Fatores de Crescimento Neural/biossíntese; Fatores de Crescimento Neural/genética; Neurônios/patologia; Esquizofrenia/patologia

Palavras-chave

aquaporin 3; copy number variant; multiple sclerosis; neurofascin155; paranodal junction; schizophrenia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Aquaporina 3 / Neurônios Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Aquaporina 3 / Neurônios Idioma: En Ano de publicação: 2018 Tipo de documento: Article