Toe dystonia in Parkinson's disease: Impact of subthalamic nucleus deep brain stimulation.
J Neurol Sci
; 392: 65-68, 2018 09 15.
Article
em En
| MEDLINE
| ID: mdl-30025235
ABSTRACT
BACKGROUND:
Off state toe dystonia (TD) is a symptom frequently encountered in Parkinson's disease (PD), but little is known about its evolution after subthalamic nucleus deep brain stimulation (STN-DBS).OBJECTIVE:
To analyze the prevalence and the evolution of TD in PD patients candidate to STN-DBS.METHODS:
Individual data of consecutive 130 PD patients who underwent STN-DBS between 2010 and 2015 were collected.RESULTS:
Data were successfully collected in 95 patients. TD affect 45.3% of the patients in our cohort. TD was present in 32.7% of patients before surgery and was alleviated by STN-DBS in 48% of the cases. Motor improvement provided by STN-DBS, levodopa-equivalent treatment diminution after surgery, disease duration or age at the time of surgery were not predictive of TD evolution. A younger age at PD diagnosis was significantly associated with TD resolution.CONCLUSION:
STN-DBS is partially efficient for TD but its evolution seems independent of significant predictive factors.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Dedos do Pé
/
Núcleo Subtalâmico
/
Estimulação Encefálica Profunda
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Distonia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article