A Global Perspective of Latent Autoimmune Diabetes in Adults.
Trends Endocrinol Metab
; 29(9): 638-650, 2018 09.
Article
em En
| MEDLINE
| ID: mdl-30041834
ABSTRACT
Latent autoimmune diabetes in adults (LADA) is characterized by the presence of islet autoantibodies and initial insulin independence, which can lead to misdiagnosis of type 2 diabetes (T2D). As such, understanding the genetic etiology of LADA could aid in more accurate diagnosis. However, there is ongoing debate regarding the exact definition of LADA, so understanding its impact in different populations when contrasted with type 1 diabetes (T1D) and T2D is one potential strategy to gain insight into its etiology. Unfortunately, the lack of consistent and thorough autoantibody screening around the world has hampered well-powered genetic studies of LADA. This review highlights recent genetic and epidemiological studies of LADA in diverse populations as well as the importance of autoantibody screening in facilitating future research.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Autoanticorpos
/
Diabetes Autoimune Latente em Adultos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article