[A New Twist on the Administration of Naldemedine for Opioid-Induced Constipation in an Outpatient].
Gan To Kagaku Ryoho
; 45(7): 1075-1079, 2018 Jul.
Article
em Ja
| MEDLINE
| ID: mdl-30042276
ABSTRACT
Opioid-induced constipation(OIC)occurs with high frequency in patients with cancer undergoing pain treatment using opioids. Osmotic or irritant laxatives are usually used to prevent OIC. Recently, naldemedine has become operational for OIC. Although naldemedine achieved the desired effect, diarrhea is a little feared from the results of clinical phase III study(V9236 clinical trial). We herein report the use of naldemedine to alleviate diarrhea and expect the improvement of the quality of the bowel habits in outpatients with cancer undergoing pain treatment using opioids.
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Base de dados:
MEDLINE
Assunto principal:
Constipação Intestinal
/
Diarreia
/
Dor do Câncer
/
Analgésicos Opioides
/
Naltrexona
/
Neoplasias
Idioma:
Ja
Ano de publicação:
2018
Tipo de documento:
Article