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Structure-activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359.
Zhang, Hang; Nielsen, Alexander L; Boesgaard, Michael W; Harpsøe, Kasper; Daly, Norelle L; Xiong, Xiao-Feng; Underwood, Christina R; Haugaard-Kedström, Linda M; Bräuner-Osborne, Hans; Gloriam, David E; Strømgaard, Kristian.
Afiliação
  • Zhang H; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark; Key Laboratory of Advanced Drug, Preparation Technologies, Ministry of Education, Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety, School of Pharmaceutical Science
  • Nielsen AL; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Boesgaard MW; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Harpsøe K; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Daly NL; Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Queensland, Australia.
  • Xiong XF; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Underwood CR; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Haugaard-Kedström LM; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Bräuner-Osborne H; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark.
  • Strømgaard K; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100, Copenhagen, Denmark. Electronic address: kristian.stromgaard@sund.ku.dk.
Eur J Med Chem ; 156: 847-860, 2018 Aug 05.
Article em En | MEDLINE | ID: mdl-30055466
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Depsipeptídeos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Depsipeptídeos Idioma: En Ano de publicação: 2018 Tipo de documento: Article