Differential regulation of ß<sub>2</sub>-adrenoceptor and adenosine A<sub>2B</sub> receptor signalling by GRK and arrestin proteins in arterial smooth muscle.

Nash, Craig A; Nelson, Carl P; Mistry, Rajendra; Moeller-Olsen, Christian; Christofidou, Elena; Challiss, R A John; Willets, Jonathon M

Differential regulation of ß₂-adrenoceptor and adenosine A_2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle.

Nash, Craig A; Nelson, Carl P; Mistry, Rajendra; Moeller-Olsen, Christian; Christofidou, Elena; Challiss, R A John; Willets, Jonathon M.

Afiliação

Nash CA; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom.
Nelson CP; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom.
Mistry R; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom.
Moeller-Olsen C; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom.
Christofidou E; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom.
Challiss RAJ; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom.
Willets JM; Department of Molecular and Cell Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7RH, United Kingdom. Electronic address: jmw23@leicester.ac.uk.

Cell Signal ; 51: 86-98, 2018 11.

Article em En | MEDLINE | ID: mdl-30075183

Assuntos

Aorta/metabolismo; Quinase 2 de Receptor Acoplado a Proteína G/fisiologia; Quinase 5 de Receptor Acoplado a Proteína G/fisiologia; Quinases de Receptores Acoplados a Proteína G/fisiologia; Músculo Liso/metabolismo; Miócitos de Músculo Liso/metabolismo; Receptor A2B de Adenosina/metabolismo; Receptores Adrenérgicos beta 2/metabolismo; beta-Arrestina 2/fisiologia; Adenilil Ciclases/metabolismo; Animais; Aorta/citologia; Arrestinas/genética; Arrestinas/fisiologia; Células Cultivadas; Quinase 2 de Receptor Acoplado a Proteína G/genética; Quinase 5 de Receptor Acoplado a Proteína G/genética; Músculo Liso/citologia; Miócitos de Músculo Liso/citologia; Ratos; Ratos Wistar; Transdução de Sinais; beta-Arrestina 2/genética

Palavras-chave

Adenosine A(2B) receptor; Arrestin; GRK; Vascular smooth muscle; ß(2)-adrenoceptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aorta / Receptores Adrenérgicos beta 2 / Miócitos de Músculo Liso / Receptor A2B de Adenosina / Quinases de Receptores Acoplados a Proteína G / Quinase 2 de Receptor Acoplado a Proteína G / Quinase 5 de Receptor Acoplado a Proteína G / Beta-Arrestina 2 / Músculo Liso Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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