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Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFß1 Axis.
Prete, Alessandro; Lo, Agnes S; Sadow, Peter M; Bhasin, Swati S; Antonello, Zeus A; Vodopivec, Danica M; Ullas, Soumya; Sims, Jennifer N; Clohessy, John; Dvorak, Ann M; Sciuto, Tracey; Bhasin, Manoj; Murphy-Ullrich, Joanne E; Lawler, Jack; Karumanchi, S Ananth; Nucera, Carmelo.
Afiliação
  • Prete A; Laboratory of Human Thyroid Cancers Preclinical and Translational Research, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Lo AS; Department of Pathology, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Sadow PM; Department of Medicine, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Bhasin SS; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Antonello ZA; Bioinformatic and Systems Biology Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Vodopivec DM; Laboratory of Human Thyroid Cancers Preclinical and Translational Research, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Ullas S; Department of Pathology, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Sims JN; Laboratory of Human Thyroid Cancers Preclinical and Translational Research, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Clohessy J; Department of Pathology, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Dvorak AM; Longwood Small Animal Imaging Facility (LSAIF), Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Sciuto T; Laboratory of Human Thyroid Cancers Preclinical and Translational Research, Division of Experimental Pathology, Cancer Research Institute (CRI), Cancer Center, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Bhasin M; Department of Pathology, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Murphy-Ullrich JE; Division of Cancer Genetics, Department of Medicine, Beth Israel Deaconess Medical School, Harvard Medical School, Boston, Massachusetts.
  • Lawler J; Department of Pathology, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Karumanchi SA; Department of Pathology, Center for Vascular Biology Research (CVBR), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Nucera C; Bioinformatic and Systems Biology Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Clin Cancer Res ; 24(23): 6078-6097, 2018 12 01.
Article em En | MEDLINE | ID: mdl-30076136
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Resistencia a Medicamentos Antineoplásicos / Pericitos / Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos / Fator de Crescimento Transformador beta1 / Vemurafenib Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Resistencia a Medicamentos Antineoplásicos / Pericitos / Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos / Fator de Crescimento Transformador beta1 / Vemurafenib Idioma: En Ano de publicação: 2018 Tipo de documento: Article