Computational fluid dynamic modeling of alternating tangential flow filtration for perfusion cell culture.

Radoniqi, Flaka; Zhang, Hu; Bardliving, Cameron L; Shamlou, Parviz; Coffman, Jon

Radoniqi, Flaka; Zhang, Hu; Bardliving, Cameron L; Shamlou, Parviz; Coffman, Jon.

Afiliação

Radoniqi F; School of Applied Life Sciences, Amgen Bioprocessing Center, Keck Graduate Institute, Claremont, California.
Zhang H; School of Applied Life Sciences, Amgen Bioprocessing Center, Keck Graduate Institute, Claremont, California.
Bardliving CL; School of Applied Life Sciences, Amgen Bioprocessing Center, Keck Graduate Institute, Claremont, California.
Shamlou P; School of Applied Life Sciences, Amgen Bioprocessing Center, Keck Graduate Institute, Claremont, California.
Coffman J; Department of Process Science, Boehringer Ingelheim, Fremont, California.

Biotechnol Bioeng ; 115(11): 2751-2759, 2018 11.

Article em En | MEDLINE | ID: mdl-30080936

Assuntos

Reatores Biológicos; Técnicas de Cultura de Células/métodos; Separação Celular/métodos; Filtração/métodos; Hidrodinâmica; Animais; Células CHO; Cricetulus

Palavras-chave

Starling flow; alternating tangential flow filtration; computational fluid dynamics; cross flow velocity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Separação Celular / Técnicas de Cultura de Células / Reatores Biológicos / Hidrodinâmica / Filtração Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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