Effects of polymorphic variation on the thermostability of heterogenous populations of CYP3A4 and CYP2C9 enzymes in solution.

Arendse, Lauren B; Blackburn, Jonathan M

Arendse, Lauren B; Blackburn, Jonathan M.

Afiliação

Arendse LB; Institute for Infectious Disease & Molecular Medicine, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, South Africa.
Blackburn JM; Institute for Infectious Disease & Molecular Medicine, Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, South Africa. jonathan.blackburn@uct.ac.za.

Sci Rep ; 8(1): 11876, 2018 08 08.

Article em En | MEDLINE | ID: mdl-30089838

Assuntos

Citocromo P-450 CYP2C9/genética; Citocromo P-450 CYP3A/genética; Polimorfismo de Nucleotídeo Único/genética; Células Cultivadas; Humanos; Cinética; Estabilidade Proteica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP3A / Citocromo P-450 CYP2C9 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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