Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.

Cao, Zhanqi; Hao, Zhaojun; Xin, Ming; Yu, Lugang; Wang, Lei; Zhang, Ying; Zhang, Xinke; Guo, Xiuli

Cao, Zhanqi; Hao, Zhaojun; Xin, Ming; Yu, Lugang; Wang, Lei; Zhang, Ying; Zhang, Xinke; Guo, Xiuli.

Afiliação

Cao Z; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China.
Hao Z; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China.
Xin M; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China.
Yu L; Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3GE, UK.
Wang L; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China.
Zhang Y; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China.
Zhang X; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China.
Guo X; Department of Pharmacology Drug Screening Platform of Shandong Province Center for Drug R&D, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China. guoxl@sdu.edu.cn.

Lab Invest ; 98(12): 1642-1656, 2018 12.

Article em En | MEDLINE | ID: mdl-30171204

Assuntos

Caderinas/metabolismo; Adesão Celular; Galectina 3/metabolismo; Regulação Neoplásica da Expressão Gênica; Receptores de Hialuronatos/metabolismo; Células A549; Animais; Movimento Celular; Feminino; Células Endoteliais da Veia Umbilical Humana; Humanos; Camundongos Endogâmicos BALB C; Camundongos Nus; Mucina-1/metabolismo; Metástase Neoplásica; Regulação para Cima; beta Catenina/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caderinas / Regulação Neoplásica da Expressão Gênica / Adesão Celular / Receptores de Hialuronatos / Galectina 3 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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