[Correlation of prostate-specific antigen with the progression and metastasis of human prostate cancer].
Zhonghua Nan Ke Xue
; 24(5): 457-461, 2018 May.
Article
em Zh
| MEDLINE
| ID: mdl-30171764
ABSTRACT
Prostate-specific antigen (PSA) is a biomarker for the diagnosis and management of prostate cancer and involved in the development of prostate cancer and/or its progression from the localized to the metastatic stage. This review presents an overview of the roles of PSA in promoting the progression and metastasis of human prostate cancer and its underlying mechanisms, including its serine protease activity, interaction with the cellular membrane receptor, and suppression of specific immune responsiveness, and also points out some of the key problems to be solved.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Antígeno Prostático Específico
Idioma:
Zh
Ano de publicação:
2018
Tipo de documento:
Article