A Parkinson's disease gene, DJ-1, regulates astrogliosis through STAT3.

Choi, Dong-Joo; Kwon, Jae-Kyung; Joe, Eun-Hye

Choi, Dong-Joo; Kwon, Jae-Kyung; Joe, Eun-Hye.

Afiliação

Choi DJ; Department of Pharmacology, Ajou University School of Medicine, South Korea; Chronic Inflammatory Disease Research Center, Ajou University School of Medicine, South Korea. Electronic address: djchoi81@ajou.ac.kr.
Kwon JK; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, South Korea.
Joe EH; Department of Pharmacology, Ajou University School of Medicine, South Korea; Chronic Inflammatory Disease Research Center, Ajou University School of Medicine, South Korea; Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, South Korea; Department of Brain Science, Ajou University School of Medicine, Worldcup-ro 164, Suwon, Kyunggi-do 16499, South Korea.

Neurosci Lett ; 685: 144-149, 2018 10 15.

Article em En | MEDLINE | ID: mdl-30171910

Assuntos

Gliose/genética; Doença de Parkinson/genética; Proteína Desglicase DJ-1/genética; Proteína Desglicase DJ-1/metabolismo; Fator de Transcrição STAT3/metabolismo; Animais; Astrócitos/metabolismo; Proteína Glial Fibrilar Ácida/metabolismo; Gliose/metabolismo; Camundongos Knockout; Doença de Parkinson/metabolismo; Fosforilação; Fator de Transcrição STAT3/genética; Transdução de Sinais/genética; Transdução de Sinais/fisiologia

Palavras-chave

Astrogliosis; DJ-1; Parkinsons disease; STAT3

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Fator de Transcrição STAT3 / Proteína Desglicase DJ-1 / Gliose Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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