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Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling.
Shigemura, Masahiko; Lecuona, Emilia; Angulo, Martín; Homma, Tetsuya; Rodríguez, Diego A; Gonzalez-Gonzalez, Francisco J; Welch, Lynn C; Amarelle, Luciano; Kim, Seok-Jo; Kaminski, Naftali; Budinger, G R Scott; Solway, Julian; Sznajder, Jacob I.
Afiliação
  • Shigemura M; Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Lecuona E; First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan.
  • Angulo M; Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Homma T; Pathophysiology Department, School of Medicine, Universidad de la República, Montevideo, Uruguay.
  • Rodríguez DA; Division of Allergology and Respiratory Medicine, Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan.
  • Gonzalez-Gonzalez FJ; Pulmonology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Me`diques, Universitat Pompeu Fabra, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), ISCiii, Barcelona, Spain.
  • Welch LC; Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Amarelle L; Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Kim SJ; Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Kaminski N; Pathophysiology Department, School of Medicine, Universidad de la República, Montevideo, Uruguay.
  • Budinger GRS; Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Solway J; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612, USA.
  • Sznajder JI; Department of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, CT 06520, USA.
Sci Transl Med ; 10(457)2018 09 05.
Article em En | MEDLINE | ID: mdl-30185650
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteína rhoA de Ligação ao GTP / Caspase 7 / Hipercapnia / Contração Muscular / Músculo Liso Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteína rhoA de Ligação ao GTP / Caspase 7 / Hipercapnia / Contração Muscular / Músculo Liso Idioma: En Ano de publicação: 2018 Tipo de documento: Article