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MEPicides: α,ß-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria.
Wang, Xu; Edwards, Rachel L; Ball, Haley; Johnson, Claire; Haymond, Amanda; Girma, Misgina; Manikkam, Michelle; Brothers, Robert C; McKay, Kyle T; Arnett, Stacy D; Osbourn, Damon M; Alvarez, Sophie; Boshoff, Helena I; Meyers, Marvin J; Couch, Robin D; Odom John, Audrey R; Dowd, Cynthia S.
Afiliação
  • Wang X; Department of Chemistry , George Washington University , Washington D.C. 20052 , United States.
  • Edwards RL; Department of Pediatrics , Washington University School of Medicine, Washington University , St. Louis , Missouri 63110 , United States.
  • Ball H; Department of Chemistry and Biochemistry , George Mason University , Manassas , Virginia 20110 , United States.
  • Johnson C; Department of Chemistry and Biochemistry , George Mason University , Manassas , Virginia 20110 , United States.
  • Haymond A; Department of Chemistry and Biochemistry , George Mason University , Manassas , Virginia 20110 , United States.
  • Girma M; Department of Chemistry and Biochemistry , George Mason University , Manassas , Virginia 20110 , United States.
  • Manikkam M; Tuberculosis Research Section, LCIM , NIAID/NIH , Bethesda , Maryland 20892 , United States.
  • Brothers RC; Department of Chemistry , George Washington University , Washington D.C. 20052 , United States.
  • McKay KT; Department of Chemistry , George Washington University , Washington D.C. 20052 , United States.
  • Arnett SD; Department of Pharmacology and Physiology , Saint Louis University , St. Louis , Missouri 63104 , United States.
  • Osbourn DM; Department of Molecular Microbiology and Immunology , Saint Louis University , St. Louis , Missouri 63104 , United States.
  • Alvarez S; Proteomics & Metabolomics Facility, Center for Biotechnology, Department of Agronomy and Horticulture , University of Nebraska-Lincoln , Lincoln , Nebraska 68588 , United States.
  • Boshoff HI; Tuberculosis Research Section, LCIM , NIAID/NIH , Bethesda , Maryland 20892 , United States.
  • Meyers MJ; Department of Pharmacology and Physiology , Saint Louis University , St. Louis , Missouri 63104 , United States.
  • Couch RD; Department of Chemistry , Saint Louis University , St. Louis , Missouri 63103 , United States.
  • Odom John AR; Department of Chemistry and Biochemistry , George Mason University , Manassas , Virginia 20110 , United States.
  • Dowd CS; Department of Pediatrics , Washington University School of Medicine, Washington University , St. Louis , Missouri 63110 , United States.
J Med Chem ; 61(19): 8847-8858, 2018 10 11.
Article em En | MEDLINE | ID: mdl-30192536
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Pró-Fármacos / Malária Falciparum / Aldose-Cetose Isomerases / Fosfomicina / Antimaláricos Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Pró-Fármacos / Malária Falciparum / Aldose-Cetose Isomerases / Fosfomicina / Antimaláricos Idioma: En Ano de publicação: 2018 Tipo de documento: Article