Metabonomics delineates allergic reactions induced by Shuang-huang-lian injection in rats using ultra performance liquid chromatography-mass spectrometry.

Gu, Yuan-Yuan; Shi, Lang; Zhang, Dan-Dan; Huang, Xin; Chen, Da-Zhong

Gu, Yuan-Yuan; Shi, Lang; Zhang, Dan-Dan; Huang, Xin; Chen, Da-Zhong.

Afiliação

Gu YY; Research Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Shi L; First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Zhang DD; Research Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Huang X; First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Chen DZ; Research Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China. Electronic address: 1259779868@qq.com.

Chin J Nat Med ; 16(8): 628-640, 2018 Aug.

Article em En | MEDLINE | ID: mdl-30197129

Assuntos

Hipersensibilidade a Drogas/etiologia; Hipersensibilidade a Drogas/urina; Medicamentos de Ervas Chinesas/efeitos adversos; Animais; Biomarcadores/urina; Cromatografia Líquida de Alta Pressão; Medicamentos de Ervas Chinesas/administração & dosagem; Histamina/urina; Masculino; Metabolômica; Ratos; Ratos Sprague-Dawley; Espectrometria de Massas em Tandem

Palavras-chave

Allergic mechanism; Biomarker; Metabolites; Metabonomics; Shuang-huang-lian injection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Hipersensibilidade a Drogas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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