Role of heme oxygenase-1 and its reaction product, carbon monoxide, in manifestation of breast cancer stem cell-like properties: Notch-1 as a putative target.

Kim, Do-Hee; Yoon, Hyo-Jin; Cha, Young-Nam; Surh, Young-Joon

Kim, Do-Hee; Yoon, Hyo-Jin; Cha, Young-Nam; Surh, Young-Joon.

Afiliação

Kim DH; a Tumor Microenvironment Global Core Research Center and Research Institute of Pharmaceutical Sciences, Seoul National University , Seoul , South Korea.
Yoon HJ; b Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology , Seoul National University , Seoul , South Korea.
Cha YN; a Tumor Microenvironment Global Core Research Center and Research Institute of Pharmaceutical Sciences, Seoul National University , Seoul , South Korea.
Surh YJ; c Department of Pharmacology and Toxicology, College of Medicine , Inha University , Incheon , South Korea.

Free Radic Res ; 52(11-12): 1336-1347, 2018 Dec.

Article em En | MEDLINE | ID: mdl-30238818

Assuntos

Neoplasias da Mama/metabolismo; Monóxido de Carbono/metabolismo; Heme Oxigenase-1/metabolismo; Células-Tronco Neoplásicas/metabolismo; Receptor Notch1/metabolismo; Neoplasias da Mama/patologia; Monóxido de Carbono/química; Feminino; Humanos; Células-Tronco Neoplásicas/patologia; Transdução de Sinais; Células Tumorais Cultivadas

Palavras-chave

Cancer stem cells; Notch-1; Nrf2; carbon monoxide; heme oxygenase-1; selfrenewal

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias da Mama / Monóxido de Carbono / Heme Oxigenase-1 / Receptor Notch1 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google