Assessment of the influence of viscoelasticity of cornea in animal ex vivo model using air-puff optical coherence tomography and corneal hysteresis.
J Biophotonics
; 12(2): e201800154, 2019 02.
Article
em En
| MEDLINE
| ID: mdl-30239154
ABSTRACT
Application of the air-puff swept source optical coherence tomography (SS-OCT) instrument to determine the influence of viscoelasticity on the relation between overall the air-puff force and corneal apex displacement of porcine corneas ex vivo is demonstrated. Simultaneous recording of time-evolution of the tissue displacement and air pulse stimulus allows obtaining valuable information related in part to the mechanical properties of the cornea. A novel approach based on quantitative analysis of the corneal hysteresis of OCT data is presented. The corneal response to the air pulse is assessed for different well-controlled intraocular pressure (IOP) levels and for the progression of cross-linking-induced stiffness of the cornea. Micrometer resolution, fast acquisition and noncontact character of the air-puff SS-OCT measurements have potential to improve the in vivo assessment of mechanical properties of the human corneas.
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Base de dados:
MEDLINE
Assunto principal:
Córnea
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Tomografia de Coerência Óptica
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Ar
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Elasticidade
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article