Identification of cartilage oligomeric matrix protein as biomarker predicting abatacept response in rheumatoid arthritis patients with insufficient response to a first anti-TNF&#945; treatment.

Nguyen, Minh Vu Chuong; Adrait, Annie; Baillet, Athan; Trocmé, Candice; Gottenberg, Jacques-Eric; Gaudin, Philippe

Identification of cartilage oligomeric matrix protein as biomarker predicting abatacept response in rheumatoid arthritis patients with insufficient response to a first anti-TNFα treatment.

Nguyen, Minh Vu Chuong; Adrait, Annie; Baillet, Athan; Trocmé, Candice; Gottenberg, Jacques-Eric; Gaudin, Philippe.

Afiliação

Nguyen MVC; Université Grenoble Alpes, GREPI, EA 7408, 38400 Saint-Martin-d'Hères, France; Sinnovial, 38000 Grenoble, France.
Adrait A; Université Grenoble Alpes, 38000 Grenoble, France; CEA, biologie à grande échelle (BIG), 38054 Grenoble, France; Inserm, U1038, 38054 Grenoble, France.
Baillet A; Université Grenoble Alpes, GREPI, EA 7408, 38400 Saint-Martin-d'Hères, France; Rheumatology department, CHU Grenoble Alpes, hôpital Sud Échirolles, 38130 Échirolles, France. Electronic address: abaillet@chu-grenoble.fr.
Trocmé C; Laboratoire de biochimie des enzymes et des protéines, pôle de biologie, CHU Grenoble Alpes, 38700 La Tronche, France.
Gottenberg JE; Department of rheumatology, national reference center for rare systemic autoimmune diseases, Strasbourg university hospital, hôpital Hautepierre, 1, avenue Molière, 67000 Strasbourg, France; CNRS, institut de biologie moléculaire et cellulaire, immunopathologie et chimie thérapeutique/laboratory of
Gaudin P; Université Grenoble Alpes, GREPI, EA 7408, 38400 Saint-Martin-d'Hères, France; Rheumatology department, CHU Grenoble Alpes, hôpital Sud Échirolles, 38130 Échirolles, France.

Joint Bone Spine ; 86(3): 401-403, 2019 05.

Article em En | MEDLINE | ID: mdl-30243783

Assuntos

Abatacepte/uso terapêutico; Antirreumáticos/uso terapêutico; Artrite Reumatoide/tratamento farmacológico; Proteína de Matriz Oligomérica de Cartilagem/sangue; Fator de Necrose Tumoral alfa/antagonistas & inibidores; Artrite Reumatoide/sangue; Artrite Reumatoide/diagnóstico; Biomarcadores/sangue; Estudos de Coortes; Feminino; Seguimentos; Humanos; Masculino; Pessoa de Meia-Idade; Estudos Prospectivos; Retratamento; Falha de Tratamento; Resultado do Tratamento; Fator de Necrose Tumoral alfa/uso terapêutico

Palavras-chave

Abatacept; Biomarkers; Prediction of response; Rheumatoid arthritis; TNF inhibitors; bDMARD

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Fator de Necrose Tumoral alfa / Antirreumáticos / Proteína de Matriz Oligomérica de Cartilagem / Abatacepte Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google