Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC-ESI-MS/MS.

Attwa, Mohamed W; Kadi, Adnan A; Darwish, Hany W; Amer, Sawsan M; Al-Shakliah, Nasser S.

Afiliação

Attwa MW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Kingdom of Saudi Arabia. mzeidan@ksu.edu.sa.
Kadi AA; Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St, Cairo, 11562, Egypt. mzeidan@ksu.edu.sa.
Darwish HW; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Kingdom of Saudi Arabia.
Amer SM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Kingdom of Saudi Arabia.
Al-Shakliah NS; Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St, Cairo, 11562, Egypt.

Chem Cent J ; 12(1): 99, 2018 Sep 24.

Article em En | MEDLINE | ID: mdl-30251155