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Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease.
Paz, Katelyn; Flynn, Ryan; Du, Jing; Qi, Jun; Luznik, Leo; Maillard, Ivan; MacDonald, Kelli P; Hill, Geoffrey R; Serody, Jonathan S; Murphy, William J; Sage, Peter T; Sharpe, Arlene H; Miklos, David; Cutler, Corey S; Koreth, John; Antin, Joseph H; Soiffer, Robert J; Ritz, Jerome; Bradner, James E; Melnick, Ari M; Blazar, Bruce R.
Afiliação
  • Paz K; Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN.
  • Flynn R; Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN.
  • Du J; Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN.
  • Qi J; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
  • Luznik L; Department of Medicine, Harvard Medical School, Boston, MA.
  • Maillard I; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, School of Medicine, Johns Hopkins University, Baltimore, MD.
  • MacDonald KP; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Hill GR; Department of Immunology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Serody JS; School of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Murphy WJ; Department of Immunology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Sage PT; School of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Sharpe AH; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC.
  • Miklos D; Department of Dermatology and.
  • Cutler CS; Department of Internal Medicine, Laboratory of Cancer Immunology, University of California Davis Medical Center, Sacramento, CA.
  • Koreth J; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA.
  • Antin JH; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA.
  • Soiffer RJ; Division of Blood and Marrow Transplantation, School of Medicine, Stanford University, Stanford, CA.
  • Ritz J; Stem Cell/Bone Marrow Transplantation Program, Division of Hematologic Malignancy, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
  • Bradner JE; Stem Cell/Bone Marrow Transplantation Program, Division of Hematologic Malignancy, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
  • Melnick AM; Stem Cell/Bone Marrow Transplantation Program, Division of Hematologic Malignancy, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
  • Blazar BR; Stem Cell/Bone Marrow Transplantation Program, Division of Hematologic Malignancy, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
Blood ; 133(1): 94-99, 2019 01 03.
Article em En | MEDLINE | ID: mdl-30279226

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bronquiolite Obliterante / Linfócitos B / Linfócitos T / Centro Germinativo / Proteínas Proto-Oncogênicas c-bcl-6 / Bibliotecas de Moléculas Pequenas / Doença Enxerto-Hospedeiro Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bronquiolite Obliterante / Linfócitos B / Linfócitos T / Centro Germinativo / Proteínas Proto-Oncogênicas c-bcl-6 / Bibliotecas de Moléculas Pequenas / Doença Enxerto-Hospedeiro Idioma: En Ano de publicação: 2019 Tipo de documento: Article