The role of PNPLA1 in &#969;-O-acylceramide synthesis and skin barrier function.

Hirabayashi, Tetsuya; Murakami, Makoto; Kihara, Akio

The role of PNPLA1 in ω-O-acylceramide synthesis and skin barrier function.

Hirabayashi, Tetsuya; Murakami, Makoto; Kihara, Akio.

Afiliação

Hirabayashi T; Department of Advanced Science for Biomolecules, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan. Electronic address: hirabayashi-tt@igakuken.or.jp.
Murakami M; Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Kihara A; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-chome, Kita-ku, Sapporo 060-0812, Japan.

Biochim Biophys Acta Mol Cell Biol Lipids ; 1864(6): 869-879, 2019 06.

Article em En | MEDLINE | ID: mdl-30290227

Assuntos

Ceramidas/metabolismo; Lipase/metabolismo; Pele/metabolismo; Animais; Diferenciação Celular/fisiologia; Epiderme/metabolismo; Humanos; Ictiose Lamelar/metabolismo; Mutação/fisiologia

Palavras-chave

Acylceramide; Ichthyosis; PNPLA1; Skin barrier; Transacylase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Ceramidas / Lipase Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Ceramidas / Lipase Idioma: En Ano de publicação: 2019 Tipo de documento: Article