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Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity.
Butera, Giovanna; Pacchiana, Raffaella; Mullappilly, Nidula; Margiotta, Marilena; Bruno, Stefano; Conti, Paola; Riganti, Chiara; Donadelli, Massimo.
Afiliação
  • Butera G; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, Verona, Italy.
  • Pacchiana R; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, Verona, Italy.
  • Mullappilly N; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, Verona, Italy.
  • Margiotta M; Food and Dug Department, University of Parma, Parma, Italy.
  • Bruno S; Food and Dug Department, University of Parma, Parma, Italy.
  • Conti P; Department of Pharmaceutical Sciences, University of Milan, Milano, Italy.
  • Riganti C; Department of Oncology, University of Torino, Torino, Italy.
  • Donadelli M; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, Verona, Italy. Electronic address: massimo.donadelli@univr.it.
Biochim Biophys Acta Mol Cell Res ; 1865(12): 1914-1923, 2018 12.
Article em En | MEDLINE | ID: mdl-30296496

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Núcleo Celular / Proteína Supressora de Tumor p53 / Carcinoma Ductal Pancreático / Desoxiglucose / Gliceraldeído-3-Fosfato Desidrogenases Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Núcleo Celular / Proteína Supressora de Tumor p53 / Carcinoma Ductal Pancreático / Desoxiglucose / Gliceraldeído-3-Fosfato Desidrogenases Idioma: En Ano de publicação: 2018 Tipo de documento: Article