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Preclinical assessment of an antibody-PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells.
Kinneer, Krista; Flynn, Matt; Thomas, Suneetha B; Meekin, John; Varkey, Reena; Xiao, Xiaodong; Zhong, Haihong; Breen, Shannon; Hynes, Paul G; Fleming, Ryan; Bezabeh, Binyam; Chen, Cui Tracy; Wetzel, Leslie; Chen, Ruoyan; Dimasi, Nazzareno; Tai, Yu-Tzu; Anderson, Kenneth C; Herbst, Ronald; Howard, Philip W; Hurt, Elaine M; Tice, David A.
Afiliação
  • Kinneer K; MedImmune, Oncology Research, Gaithersburg, MD, USA. kinneerk@medimmune.com.
  • Flynn M; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Thomas SB; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Meekin J; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Varkey R; MedImmune, Antibody Discovery and Protein Engineering, Gaithersburg, MD, USA.
  • Xiao X; MedImmune, Antibody Discovery and Protein Engineering, Gaithersburg, MD, USA.
  • Zhong H; Bristol-Myers Squibb, Redwood City, CA, USA.
  • Breen S; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Hynes PG; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Fleming R; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Bezabeh B; Cell Medica, London, UK.
  • Chen CT; MedImmune, Antibody Discovery and Protein Engineering, Gaithersburg, MD, USA.
  • Wetzel L; MedImmune, Antibody Discovery and Protein Engineering, Gaithersburg, MD, USA.
  • Chen R; Salubris Biotherapeutics, Gaithersburg, MD, USA.
  • Dimasi N; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Tai YT; MedImmune, Oncology Research, Gaithersburg, MD, USA.
  • Anderson KC; MedImmune, Biosuperiors, Gaithersburg, MD, USA.
  • Herbst R; MedImmune, Antibody Discovery and Protein Engineering, Gaithersburg, MD, USA.
  • Howard PW; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Hurt EM; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Tice DA; MedImmune, Oncology Research, Gaithersburg, MD, USA.
Leukemia ; 33(3): 766-771, 2019 03.
Article em En | MEDLINE | ID: mdl-30315237

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Células-Tronco / Benzodiazepinas / Antígeno de Maturação de Linfócitos B / Anticorpos / Mieloma Múltiplo Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirróis / Células-Tronco / Benzodiazepinas / Antígeno de Maturação de Linfócitos B / Anticorpos / Mieloma Múltiplo Idioma: En Ano de publicação: 2019 Tipo de documento: Article