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Introducing an expanded CAG tract into the huntingtin gene causes a wide spectrum of ultrastructural defects in cultured human cells.
Morozova, Ksenia N; Suldina, Lyubov A; Malankhanova, Tuyana B; Grigor'eva, Elena V; Zakian, Suren M; Kiseleva, Elena; Malakhova, Anastasia A.
Afiliação
  • Morozova KN; Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia.
  • Suldina LA; Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia.
  • Malankhanova TB; Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia.
  • Grigor'eva EV; Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia.
  • Zakian SM; Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia.
  • Kiseleva E; E.Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russia.
  • Malakhova AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia.
PLoS One ; 13(10): e0204735, 2018.
Article em En | MEDLINE | ID: mdl-30332437
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Expansão das Repetições de Trinucleotídeos / Proteínas Mutantes / Proteína Huntingtina Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Expansão das Repetições de Trinucleotídeos / Proteínas Mutantes / Proteína Huntingtina Idioma: En Ano de publicação: 2018 Tipo de documento: Article