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Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells.
Nigro, Cecilia; Leone, Alessia; Longo, Michele; Prevenzano, Immacolata; Fleming, Thomas H; Nicolò, Antonella; Parrillo, Luca; Spinelli, Rosa; Formisano, Pietro; Nawroth, Peter P; Beguinot, Francesco; Miele, Claudia.
Afiliação
  • Nigro C; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Leone A; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Longo M; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Prevenzano I; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Fleming TH; Department of Medicine I and Clinical Chemistry, Heidelberg University Hospital, Heidelberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.
  • Nicolò A; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Parrillo L; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Spinelli R; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Formisano P; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Nawroth PP; Department of Medicine I and Clinical Chemistry, Heidelberg University Hospital, Heidelberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.
  • Beguinot F; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
  • Miele C; URT of the Institute of Experimental Endocrinology and Oncology "G. Salvatore", National Council of Research, Naples, Italy; Department of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy. Electronic address: c.miele@ieos.cnr.it.
Biochim Biophys Acta Mol Basis Dis ; 1865(1): 73-85, 2019 01.
Article em En | MEDLINE | ID: mdl-30342159

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aorta / Fosfoproteínas / Aldeído Pirúvico / Proteínas de Homeodomínio / Células Endoteliais / Indutores da Angiogênese / Lactoilglutationa Liase Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aorta / Fosfoproteínas / Aldeído Pirúvico / Proteínas de Homeodomínio / Células Endoteliais / Indutores da Angiogênese / Lactoilglutationa Liase Idioma: En Ano de publicação: 2019 Tipo de documento: Article