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Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension.
Ji, Yingjie; Yiorkas, Andrianos M; Frau, Francesca; Mook-Kanamori, Dennis; Staiger, Harald; Thomas, E Louise; Atabaki-Pasdar, Naeimeh; Campbell, Archie; Tyrrell, Jessica; Jones, Samuel E; Beaumont, Robin N; Wood, Andrew R; Tuke, Marcus A; Ruth, Katherine S; Mahajan, Anubha; Murray, Anna; Freathy, Rachel M; Weedon, Michael N; Hattersley, Andrew T; Hayward, Caroline; Machann, Jürgen; Häring, Hans-Ulrich; Franks, Paul; de Mutsert, Renée; Pearson, Ewan; Stefan, Norbert; Frayling, Timothy M; Allebrandt, Karla V; Bell, Jimmy D; Blakemore, Alexandra I; Yaghootkar, Hanieh.
Afiliação
  • Ji Y; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Yiorkas AM; Section of Investigative Medicine, Imperial College London, London, U.K.
  • Frau F; Department of Life Sciences, Brunel University London, Uxbridge, U.K.
  • Mook-Kanamori D; Translational Medicine and Early Development, TMED Translational Informatics, Sanofi, Frankfurt am Main, Germany.
  • Staiger H; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Thomas EL; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
  • Atabaki-Pasdar N; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
  • Campbell A; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Tyrrell J; Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Jones SE; Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, U.K.
  • Beaumont RN; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.
  • Wood AR; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, U.K.
  • Tuke MA; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, U.K.
  • Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Mahajan A; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Murray A; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Freathy RM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Hattersley AT; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Hayward C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, U.K.
  • Machann J; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Häring HU; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • Franks P; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, U.K.
  • de Mutsert R; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.
  • Pearson E; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, U.K.
  • Stefan N; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
  • Frayling TM; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Allebrandt KV; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
  • Bell JD; German Center for Diabetes Research (DZD), Tübingen, Germany.
  • Blakemore AI; Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Angiology, Nephrology and Clinical Chemistry, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Yaghootkar H; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.
Diabetes ; 68(1): 207-219, 2019 01.
Article em En | MEDLINE | ID: mdl-30352878
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Diabetes Mellitus Tipo 2 / Cardiopatias Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Diabetes Mellitus Tipo 2 / Cardiopatias Idioma: En Ano de publicação: 2019 Tipo de documento: Article