Rapid degradation of progressive ankylosis protein (ANKH) in craniometaphyseal dysplasia.

Kanaujiya, Jitendra; Bastow, Edward; Luxmi, Raj; Hao, Zhifang; Zattas, Dimitrios; Hochstrasser, Mark; Reichenberger, Ernst J; Chen, I-Ping

Kanaujiya, Jitendra; Bastow, Edward; Luxmi, Raj; Hao, Zhifang; Zattas, Dimitrios; Hochstrasser, Mark; Reichenberger, Ernst J; Chen, I-Ping.

Afiliação

Kanaujiya J; Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, CT, 06030, United States.
Bastow E; Center for Regenerative Medicine and Skeletal Development, Department of Reconstructive Sciences, University of Connecticut Health, Farmington, CT, 06030, United States.
Luxmi R; Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, CT, 06030, United States.
Hao Z; Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, CT, 06030, United States.
Zattas D; Program in Structural Biology, Sloan Kettering Institute, New York, NY, 10065, United States.
Hochstrasser M; Department of Molecular Biophysics and Biochemistry, Department of Molecular, Cellular and Development Biology, Yale University, New Haven, CT, 06520, United States.
Reichenberger EJ; Center for Regenerative Medicine and Skeletal Development, Department of Reconstructive Sciences, University of Connecticut Health, Farmington, CT, 06030, United States.
Chen IP; Department of Oral Health and Diagnostic Sciences, School of Dental Medicine, University of Connecticut Health, Farmington, CT, 06030, United States. ipchen@uchc.edu.

Sci Rep ; 8(1): 15710, 2018 10 24.

Article em En | MEDLINE | ID: mdl-30356088

Assuntos

Doenças do Desenvolvimento Ósseo/etiologia; Anormalidades Craniofaciais/etiologia; Hiperostose/etiologia; Hipertelorismo/etiologia; Proteínas de Transporte de Fosfato/metabolismo; Animais; Doenças do Desenvolvimento Ósseo/genética; Células Cultivadas; Anormalidades Craniofaciais/genética; Humanos; Hiperostose/genética; Hipertelorismo/genética; Camundongos; Mutação; Proteínas de Transporte de Fosfato/genética; Complexo de Endopeptidases do Proteassoma/metabolismo; Estabilidade Proteica; Ratos; Saccharomyces cerevisiae; Ubiquitinação

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças do Desenvolvimento Ósseo / Hiperostose / Anormalidades Craniofaciais / Proteínas de Transporte de Fosfato / Hipertelorismo Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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