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Positive association of PIK3CA mutation with KRAS mutation but not BRAF mutation in colorectal cancer suggests co-selection is gene specific but not pathway specific.
Susanti, Susanti; Fadhil, Wakkas; Murtaza, Shamayal; Hassall, James C; Ebili, Henry O; Oniscu, Anca; Ilyas, Mohammad.
Afiliação
  • Susanti S; Molecular Pathology Group, Unit of Academic Molecular Pathology, Division of Cancer and Stem Cell, School of Medicine, University of Nottingham, Queen's Medical Centre Campus, Nottingham, UK.
  • Fadhil W; Deparment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Muhammadiyah Purwokerto, Central Java, Indonesia.
  • Murtaza S; Nottingham Molecular Pathology Node, University of Nottingham, Queen's Medical Centre Campus, Nottingham, UK.
  • Hassall JC; Molecular Pathology Group, Unit of Academic Molecular Pathology, Division of Cancer and Stem Cell, School of Medicine, University of Nottingham, Queen's Medical Centre Campus, Nottingham, UK.
  • Ebili HO; Nottingham Molecular Pathology Node, University of Nottingham, Queen's Medical Centre Campus, Nottingham, UK.
  • Oniscu A; Molecular Pathology Group, Unit of Academic Molecular Pathology, Division of Cancer and Stem Cell, School of Medicine, University of Nottingham, Queen's Medical Centre Campus, Nottingham, UK.
  • Ilyas M; Molecular Pathology Group, Unit of Academic Molecular Pathology, Division of Cancer and Stem Cell, School of Medicine, University of Nottingham, Queen's Medical Centre Campus, Nottingham, UK.
J Clin Pathol ; 72(3): 263-264, 2019 03.
Article em En | MEDLINE | ID: mdl-30361395

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Proteínas Proto-Oncogênicas p21(ras) / Proteínas Proto-Oncogênicas B-raf / Classe I de Fosfatidilinositol 3-Quinases / Mutação Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Proteínas Proto-Oncogênicas p21(ras) / Proteínas Proto-Oncogênicas B-raf / Classe I de Fosfatidilinositol 3-Quinases / Mutação Idioma: En Ano de publicação: 2019 Tipo de documento: Article