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Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.
Gong, Xueqian; Du, Jian; Parsons, Stephen H; Merzoug, Farhana F; Webster, Yue; Iversen, Philip W; Chio, Li-Chun; Van Horn, Robert D; Lin, Xi; Blosser, Wayne; Han, Bomie; Jin, Shaoling; Yao, Sufang; Bian, Huimin; Ficklin, Chris; Fan, Li; Kapoor, Avnish; Antonysamy, Stephen; Mc Nulty, Ann M; Froning, Karen; Manglicmot, Danalyn; Pustilnik, Anna; Weichert, Kenneth; Wasserman, Stephen R; Dowless, Michele; Marugán, Carlos; Baquero, Carmen; Lallena, María José; Eastman, Scott W; Hui, Yu-Hua; Dieter, Matthew Z; Doman, Thompson; Chu, Shaoyou; Qian, Hui-Rong; Ye, Xiang S; Barda, David A; Plowman, Gregory D; Reinhard, Christoph; Campbell, Robert M; Henry, James R; Buchanan, Sean G.
Afiliação
  • Gong X; Eli Lilly and Company, Indianapolis, Indiana.
  • Du J; Eli Lilly and Company, Indianapolis, Indiana.
  • Parsons SH; Eli Lilly and Company, Indianapolis, Indiana.
  • Merzoug FF; Eli Lilly and Company, Indianapolis, Indiana.
  • Webster Y; Eli Lilly and Company, Indianapolis, Indiana.
  • Iversen PW; Eli Lilly and Company, Indianapolis, Indiana.
  • Chio LC; Eli Lilly and Company, Indianapolis, Indiana.
  • Van Horn RD; Eli Lilly and Company, Indianapolis, Indiana.
  • Lin X; Eli Lilly and Company, Indianapolis, Indiana.
  • Blosser W; Eli Lilly and Company, Indianapolis, Indiana.
  • Han B; Eli Lilly and Company, Indianapolis, Indiana.
  • Jin S; Eli Lilly and Company, Indianapolis, Indiana.
  • Yao S; Eli Lilly and Company, Indianapolis, Indiana.
  • Bian H; Eli Lilly and Company, Indianapolis, Indiana.
  • Ficklin C; Eli Lilly and Company, Indianapolis, Indiana.
  • Fan L; Eli Lilly and Company, Indianapolis, Indiana.
  • Kapoor A; Eli Lilly and Company, Indianapolis, Indiana.
  • Antonysamy S; Eli Lilly and Company, Discovery Chemistry Research and Technologies, Lilly Biotechnology Center, San Diego, California.
  • Mc Nulty AM; Eli Lilly and Company, Indianapolis, Indiana.
  • Froning K; Eli Lilly and Company, Discovery Chemistry Research and Technologies, Lilly Biotechnology Center, San Diego, California.
  • Manglicmot D; Eli Lilly and Company, Discovery Chemistry Research and Technologies, Lilly Biotechnology Center, San Diego, California.
  • Pustilnik A; Eli Lilly and Company, Discovery Chemistry Research and Technologies, Lilly Biotechnology Center, San Diego, California.
  • Weichert K; Eli Lilly and Company, Discovery Chemistry Research and Technologies, Lilly Biotechnology Center, San Diego, California.
  • Wasserman SR; Eli Lilly and Company, Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois.
  • Dowless M; Eli Lilly and Company, Indianapolis, Indiana.
  • Marugán C; Eli Lilly and Company, Lilly Research Laboratories, Avenida de la Industria, Alcobendas, Spain.
  • Baquero C; Eli Lilly and Company, Lilly Research Laboratories, Avenida de la Industria, Alcobendas, Spain.
  • Lallena MJ; Eli Lilly and Company, Lilly Research Laboratories, Avenida de la Industria, Alcobendas, Spain.
  • Eastman SW; Eli Lilly and Company, Alexandria Center for Life Sciences, New York, New York.
  • Hui YH; Eli Lilly and Company, Indianapolis, Indiana.
  • Dieter MZ; Eli Lilly and Company, Indianapolis, Indiana.
  • Doman T; Eli Lilly and Company, Indianapolis, Indiana.
  • Chu S; Eli Lilly and Company, Indianapolis, Indiana.
  • Qian HR; Eli Lilly and Company, Indianapolis, Indiana.
  • Ye XS; Eli Lilly and Company, Indianapolis, Indiana.
  • Barda DA; Eli Lilly and Company, Indianapolis, Indiana.
  • Plowman GD; Eli Lilly and Company, Indianapolis, Indiana.
  • Reinhard C; Eli Lilly and Company, Indianapolis, Indiana.
  • Campbell RM; Eli Lilly and Company, Indianapolis, Indiana.
  • Henry JR; Eli Lilly and Company, Indianapolis, Indiana.
  • Buchanan SG; Eli Lilly and Company, Indianapolis, Indiana. buchananse@lilly.com.
Cancer Discov ; 9(2): 248-263, 2019 02.
Article em En | MEDLINE | ID: mdl-30373917
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Ubiquitina-Proteína Ligases / Inibidores Enzimáticos / Carcinoma de Pequenas Células do Pulmão / Proteínas de Ligação a Retinoblastoma / Pontos de Checagem do Ciclo Celular / Pontos de Checagem da Fase M do Ciclo Celular / Aurora Quinase A Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Ubiquitina-Proteína Ligases / Inibidores Enzimáticos / Carcinoma de Pequenas Células do Pulmão / Proteínas de Ligação a Retinoblastoma / Pontos de Checagem do Ciclo Celular / Pontos de Checagem da Fase M do Ciclo Celular / Aurora Quinase A Idioma: En Ano de publicação: 2019 Tipo de documento: Article