The influence of the dT.dG mispair on the activity of the human DNA(cytosine-5)methyltransferase.
Biochem Biophys Res Commun
; 146(2): 596-602, 1987 Jul 31.
Article
em En
| MEDLINE
| ID: mdl-3039984
ABSTRACT
Synthetic oligodeoxynucleotides containing a dT.dG mispair at a centrally located d(pCG) dimer are methylated at a moderate rate by highly purified human DNA(cytosine-5)methyltransferase (E.C. 2.1.1.37). The presence of a mispaired dT in one strand induced the enzyme to preferentially methylate the opposite strand.
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Base de dados:
MEDLINE
Assunto principal:
Timidina
/
DNA
/
Desoxiguanosina
/
DNA (Citosina-5-)-Metiltransferases
Idioma:
En
Ano de publicação:
1987
Tipo de documento:
Article